Their crime can break a heart because it took the life of a toddler.
"Most people have said this one of the most horrible set of circumstances that they have seen in their career, as far how their children house," US Marshall Dennis J. Erby said.
The Barretos are charged with manslaughter for the death of their 2 year old daughter.
They're also accused of forcing their other seven adopted Guatemalan children to live in a trailer home filled with needles and cockroaches.
The couples had a trial set to begin 2009 but they fled.
"They have been sighted in California. We have had sightings in Mexico, had some sightings in TN. I think some of the better intel has been in the California area," Erby said.
Sightings but no arrest, so the us marshals service added Janet and Ramone Barreto to its top 15 national fugitive list.
"It makes people aware of the case who may not have been aware at some point in time. With the reward money up to $25,000 that gives us an opportunity to hopefully get leads that we had not had to explore," Erby said.
The Barreto's are resourceful in avoiding capture.
They have been known to sell bootleg DVDs and CDs to make cash, and pan handle for loose change.
Ramon has ties to Mexico and they may have gone there to get treatment for Janet's diabetes.
"Let's just put it this way, they have been able to avoid capture so far but hopefully with this effort, we can bring that to a conclusion as well," Erby said.